Mouse Secondary Antibodies
Biotium Primary Antibody Methicillin Resistant Staphylococcus Aureus 332/423 CF740 1/EA
Staphylococcal enterotoxins represent a group of proteins which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome The illness characterized by high fever hypotension diarrhea shock and in some cases death Their molecular masses range between 27 and 30 kDa At present seven enterotoxins are known namely A B C1 C2 C3 D and E Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cysteine located in the middle of the polypeptide chain which form the so called cysteine loop Enterotoxins are extremely potent activator of T cells stimulating the production and secretion of various cytokines which mediate many of the toxic effects of these substances Enterotoxins are super antigens inducing polyclonal T cell activation by binding to the TCR and to the alpha chain of the MHC II molecule simultaneously x000D x000D Primary antibodies are
Biotium Primary Antibody Pseudomonas Aeruginosa Serotype 6C 1200/472 CF740 1/EA
This antibody is specific for serotype 6C and does not react with other species Pseudomonas aeruginosa is Gram-negative aerobic rod-shaped bacteria with unipolar motility An opportunistic human pathogen P aeruginosa is also an opportunistic pathogen of plants P aeruginosa bacteria are clinically important because they are resistant to most antibiotics and they are capable of surviving in conditions that few other organisms can tolerate Pseudomonas is often encountered in hospital and clinical work because it is a major cause of hospital acquired (nosocomial) infections Its main targets are immuno-compromised individuals burn victims and individuals on respirators or with indwelling catheters Additionally these pathogens colonize the lungs of cystic fibrosis patients P aeruginosa is often identified by its pearlescent appearance and grape-like odor in vitro Definitive clinical identification of P aeruginosa includes identifying the production of both pyocyanin and fluorescein as well
Biotium Primary Antibody Major Vault Protein 1032 CF740 1/EA
Recognizes a protein of 104 kDa-110 kDa characterized as major vault protein (MVP) Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells They have a complex morphology including several small molecules of RNA but a single protein species The MVP accounts for greater than 70% of their mass Their shape is reminiscent of the nucleopore central plug Treatment of cells with estradiol increases the amount of MVP in nuclear extract The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate Antibodies to estrogen progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP MVP is overexpressed in many neoplastic tissues and cell lines Expression of MVP predicts a poor response to chemotherapy Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and